Blanchett says she is "serious about giving up acting" as there are "lots of things I want to do with my life".
The 55-year-old is preparing to star in her first radio drama, BBC Radio 4's The Fever, and she told the Radio Times that she is still not totally comfortable with being a celebrity.
"My family roll their eyes every time I say it, but I mean it," she said.
"I am serious about giving up acting. (There are) a lot of things I want to do with my life."
The Australian most recently starred in the spy thriller Black Bag (2025), and has won two Oscars for best supporting actress in The Aviator (2005) and best actress in Blue Jasmine (2013).
She added about her experience of being a celebrity: "When you go on a talk show, or even here now, and then you see soundbites of things you've said, pulled out and italicised, they sound really loud. I'm not that person.
"I make more sense in motion - it's been a long time to remotely get comfortable with the idea of being photographed.
"I've always felt like I'm on the periphery of things, so I'm always surprised when I belong anywhere. I go with curiosity into whatever environment that I'm in, not expecting to be accepted or welcomed.
"I've spent a lifetime getting comfortable with the feeling of being uncomfortable."
With AAP.