‘Luigi: The Musical’ is centred around 26-year-old Mangione, the Ivy League graduate who has been accused of killing UnitedHealthcare CEO Brian Thompson, 50, outside a Hilton hotel in New York City in December 2024.

The show’s website describes the show as a “campy, surreal, funny, and “emotionally honest" take on why society has been so obsessed with this case.

"Our hope is that Luigi: the Musical makes people laugh---and think. We're not here to make moral proclamations. We're here to explore, with humor and heart, how it feels to live through a time when the systems we're supposed to trust have stopped feeling trustworthy,” the website reads.

It imagines Mangione “sharing a prison with real-life inmates Sam Bankman-Fried and Sean ‘Diddy’ Combs.”

The creators wrote that they “do not condone violence, sexual assault, or pedophilia in any form. This musical, in fact, serves as a critique of these men and the institutions that enabled them.

“Our characters reflect three institutions of modern disillusionment: healthcare, tech and Hollywood,” the website reads.

“Each represents a pillar of American life where public trust has eroded and where people increasingly feel betrayed, exploited, or abandoned.

“By placing these forces in one absurd prison cell, we’re offering a mirror to our moment: campy, surreal and funny, but also emotionally honest.”

Mangione has pleaded not guilty to federal charges of gunning down US health insurance executive Brian Thompson, a day after prosecutors formally stated their intent to seek the death penalty.

Mangione previously pleaded not guilty to a separate set of New York state charges over the December 4 killing of Thompson, the former CEO of UnitedHealth Group's insurance unit UnitedHealthcare.