ARL Commission chairman Peter V'landys said it was "full steam ahead".
"It's great relief for the fans ... it will be a game for the ages," he said.
Postponing the game and shifting it to Townsville has been an option if Brisbane was locked down at the last minute.
Fears of a postponement or relocation of Sunday's historic first decider at Suncorp Stadium were tempered after Queensland recorded two new locally-acquired cases a day earlier.
Crowd numbers have already been cut from 52,000 to 39,000 and that could be dropped even further depending on the latest case numbers.
Queensland has dodged a lockdown so far this week after cases of community transmission was detected in the state on Tuesday.
The call came after Queensland suburbs North Lakes, Kippa-Ring and the area of the Brisbane Airport were named as new exposure sites and classified as "moderate to low risk".
Fans will be able to get jabbed at pop-up vaccination clinics around Suncorp Stadium before the decider.
Kick-off is scheduled for 6.30pm local time (7.30pm AEDT).
There are now 25 active COVID-19 cases in Queensland.
Two overseas-acquired cases were detected in hotel quarantine on Saturday.