| Date | Grand Prix | Circuit |
| 28 March | Qatar* | Losail International Circuit |
| 11 April | Republica Argentina | Termas de Rio Hondo |
| 18 April | Americas | Circuit of The Americas |
| 02 May | Spain | Circuito de Jerez-Ángel Nieto |
| 16 May | France | Le Mans |
| 30 May | Italy | Autodromo del Mugello |
| 06 June | Catalunya | Barcelona - Catalunya |
| 20 June | Germany | Sachsenring |
| 27 June | Netherlands | TT Circuit Assen |
| 11 July | Finland** | KymiRing |
| GP Date TBD | To be decided | Circuit to be decided |
| 15 August | Austria | Red Bull Ring-Spielberg |
| 29 August | Great Britain | Silverstone Circuit |
| 12 September | Aragón | MotorLand Aragón |
| 19 September | San Marino e della Riviera di Rimini | Misano World Circuit Marco Simoncelli |
| 03 October | Japan | Twin Ring Motegi |
| 10 October | Thailand | Chang International Circuit |
| 24 October | Australia | Philip Island |
| 31 October | Malaysia | Sepang International Circuit |
| 14 November | Comunitat Valenciana | Comunitat Valenciana-Ricardo Tormo |
* Evening Race
** Subject to the Homologation
All dates, events and the attendance of spectators are subject to the evolution of the pandemic and the approval of the corresponding Governments and authorities.
Reserve Grand Prix venues:
| Grand Prix | Circuit |
| Portugal | Algarve International Circuit |
| Indonesia** | Mandalika International Street Circuit |
Tune in to Bold and 10 play in 2021 for the MotoGP Season
